1. #4 Ohio State at #5 Indiana Time: 12:00 PM ET Spread: Ohio State -3.5 Over/Under: 51.5 Matchup: A top-five Big Ten showdown with major College Football Playoff implications. Indiana has home-field advantage in what could be the game of the week. 2. #2 Notre Dame at #8 BYU Time: 7:30 PM ET Spread: Notre Dame -10.5 Over/Under: 46.5 Matchup: Notre Dame travels to Provo for a major ranked matchup against BYU. The lower total points toward a potentially more defensive game. 3.

Week 6 brings a loaded college football slate with five games standing above the rest. #2 Georgia at #6 Alabama — Alabama -1.5, O/U 54.5: Two undefeated SEC powers collide in the weekend’s biggest matchup. #1 Texas vs. Oklahoma — Texas -8.5, O/U 39.5: The Red River Rivalry returns with Texas favored in a game that could have major playoff implications. #21 UCLA at #13 Oregon — Oregon -11.5, O/U 59.5: Oregon looks to protect home turf against a ranked UCLA squad. #10 LSU at